Scanning NSE · BSE · NYSE · NASDAQ

Ionis Pharmaceuticals shares plunge 26.5% after Q3 revenue miss

The biotech’s stock tumbled after third-quarter results showed a narrowing net loss and rising revenue, yet the company failed to meet analyst estimates.

The biotech’s stock tumbled after third-quarter results showed a narrowing net loss and rising revenue, yet the company failed to meet analyst estimates. Published 2026-11-09 by Falling Shares.

| By Falling Shares Intelligence, edited by Wung Thomas, Editor-in-Chief

Scope and content: The original finding aid described this as: Capture Date: 7/24/1980 Photographer: DONALD HUEBLER Keywords: c1980_03700s 1980_03728.jpg Larsen Scan Location Build
Scope and content: The original finding aid described this as: Capture Date: 7/24/1980 Photographer: DONALD HUEBLER Keywords: c1980_03700s 1980_03728.jpg Larsen Scan Location Build Credit: Unknown author Unknown author or not provided / Wikimedia Commons (Public domain) - https://commons.wikimedia.org/wiki/File:EXTERIORS_AND_INTERIORS_OF_THE_SPACE_POWER_RESEARCH_LABORATORY_SPRL_-_ENERGY_CONVERSION_LABORATORY_ECL_-_REDOX_-_RESEARCH_ANALYSIS_CENTER_RAC_-_BASIC_MATERIALS_LABORATORY_BML_-_VERTICAL_LIFT_FACILITY_VLF_-_NARA_-_17497241.jpg / Unknown author Unknown author or not provided / Public domain

Written by Falling Shares Intelligence, our automated newsroom, from the public sources listed below and live market data. Every figure is checked against that material before publication, but the story has not been reviewed by a human editor. Check the linked sources before relying on it, and report errors to info@fallingshares.com.

Ionis Pharmaceuticals shares fell 26.53% on Monday after the company reported third-quarter earnings that missed revenue estimates, despite a narrower net loss and maintained 2026 guidance.

Q3 results miss revenue estimates

Ionis Pharmaceuticals reported a third-quarter net loss that narrowed compared to the prior year, while revenue increased, according to MT Newswires. The company also maintained its revenue guidance for 2026. However, Zacks reported that the biotech missed revenue estimates for the quarter.

The Associated Press provided a snapshot of the earnings, noting the mixed nature of the release. Despite the improved profitability metrics, the market reaction was sharply negative, with the stock sliding in the latest session.

Stock under pressure for months

The fall leaves the stock 31.4% lower over the past five days and 37.6% down over the last month. Over the past year, shares have lost 61.9% of their value, sitting 67.3% below their 52-week high of $86.74.

Falling Shares rates the stock Unstable, citing an annualised volatility of 78.5% compared to 14.2% for the benchmark. By Falling Shares' measure, almost all of the move was company-specific, with the market and sector contributions being negligible.

Wung Thomas, Editor-in-Chief: wungthomas@fallingshares.com. General enquiries and corrections: info@fallingshares.com